Regeneron COVID-19 Dashboard
Enabled by data from GISAID

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Welcome to the Regeneron COVID-19 Dashboard

This dashboard contains aggregated information on SARS-CoV-2 (hCoV-19) genomes and associated patient metadata, gathered in partnership with the GISAID initiative.

The goal of the dashboard is to enable scientists to understand the evolution of this emerging coronavirus by monitoring and displaying pertinent information. For example, the dashboard displays the novel mutations in SARS-CoV-2 (hCoV-19) genomes across time and geographical location, which facilitates the identification of a mutation that may increase transmission or virulence.

In addition, there is de-identified patient demographic information such as country of origin, patient status, and age, which provides further insights into the populations most susceptible to the virus.

13,512,186

SARS-CoV-2 (hCoV-19) genomes

November 21, 2022

02:32 AM ET

Last data update

Top Lineages Per Country (Past 12 Weeks)

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  • Top* Lineages (Past 12 Weeks)

  • Europe
  • North America
  • Asia
  • Oceania
  • South America
  • Africa
  • US State
Lineage WHO Label Country Percent Lineage Count Total Count
BA.5.2BA.5.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Crimea 76% 62 82
BA.5.2BA.5.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Russia 62% 3,417 5,542
BA.5.2BA.5.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Estonia 43% 417 965
BA.5.2BA.5.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Turkey 37% 881 2,412
BA.5.2BA.5.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Republic of Serbia 31% 49 160
BA.5.2BA.5.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Bulgaria 29% 65 222
BA.5.2BA.5.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Finland 26% 212 824
BA.5.1BA.5.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (89%), L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Romania 25% 154 618
BA.5.2BA.5.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Slovakia 23% 322 1,391
BA.5.1BA.5.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (89%), L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Portugal 22% 374 1,692
BA.5.2.1BA.5.2.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Greece 21% 15 72
BA.5.2BA.5.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Slovenia 21% 600 2,887
BA.5.2BA.5.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Croatia 20% 420 2,057
BA.5.2BA.5.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Ukraine 20% 13 64
BA.5.2BA.5.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Poland 19% 389 2,040
BA.5.1BA.5.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (89%), L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Slovenia 19% 535 2,887
BA.5.2BA.5.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Germany 18% 7,977 43,283
BA.5.1BA.5.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (89%), L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Finland 18% 150 824
BA.5.2BA.5.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Greece 18% 13 72
BF.7BF.7 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, R346T, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Belgium 18% 1,259 7,025
BA.5.2BA.5.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Czechia 18% 658 3,734
BA.5.2BA.5.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Norway 17% 214 1,233
BA.5.2BA.5.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Switzerland 17% 824 4,754
BA.5.2BA.5.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Romania 17% 106 618
BA.5.1BA.5.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (89%), L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Republic of Serbia 17% 27 160
BA.5.2BA.5.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Iceland 17% 130 774
BA.5.2BA.5.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Austria 17% 747 4,524
BA.5.2BA.5.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Italy 16% 1,261 7,704
BA.5.1BA.5.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (89%), L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Spain 16% 853 5,230
BA.5.1BA.5.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (89%), L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Croatia 16% 329 2,057
BA.5.2BA.5.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Sweden 16% 1,485 9,288
BA.5.2BA.5.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Portugal 16% 265 1,692
BA.5.2.1BA.5.2.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Bulgaria 15% 34 222
BA.5.1BA.5.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (89%), L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Slovakia 15% 208 1,391
BA.5.2BA.5.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Ireland 15% 559 3,739
BA.5.1BA.5.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (89%), L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Bulgaria 15% 33 222
BA.2.75BA.2.75 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339H, R346T (55%), S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, G446S, N460K, S477N, T478K, E484A, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24- (87%), P25- (87%), P26- (87%), A27S (88%), G142D (84%), K147E, W152R, F157L, I210V, V213G, G257S, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Austria 14% 646 4,524
BA.5.2BA.5.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Denmark 14% 4,926 34,533
BF.7BF.7 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, R346T, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Luxembourg 14% 651 4,602
BA.5.2.1BA.5.2.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Ukraine 14% 9 64
BA.5.1BA.5.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (89%), L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Poland 14% 286 2,040
BA.5.2.1BA.5.2.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Croatia 14% 285 2,057
BA.5.2.1BA.5.2.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Republic of Serbia 14% 22 160
BA.5.2.1BA.5.2.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Finland 14% 113 824
BA.5.1BA.5.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (89%), L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Italy 14% 1,050 7,704
BA.5.2.1BA.5.2.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Turkey 14% 328 2,412
BA.5.2.1BA.5.2.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Romania 13% 83 618
BA.5.2BA.5.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Netherlands 13% 1,075 8,028
BA.2.75BA.2.75 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339H, R346T (55%), S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, G446S, N460K, S477N, T478K, E484A, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24- (87%), P25- (87%), P26- (87%), A27S (88%), G142D (84%), K147E, W152R, F157L, I210V, V213G, G257S, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Liechtenstein 13% 22 166
BA.5.1BA.5.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (89%), L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Netherlands 13% 1,061 8,028
BA.5.2BA.5.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron France 13% 3,485 26,746
BA.5.2BA.5.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron United Kingdom 13% 5,434 41,862
BA.5.2BA.5.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Luxembourg 13% 593 4,602
BA.5.2.1BA.5.2.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Slovakia 13% 178 1,391
BA.5.1BA.5.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (89%), L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron France 13% 3,412 26,746
BA.5.1BA.5.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (89%), L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Luxembourg 13% 587 4,602
BA.5.1BA.5.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (89%), L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Germany 13% 5,467 43,283
BA.5.2BA.5.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Spain 13% 660 5,230
BA.5.1BA.5.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (89%), L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Czechia 13% 470 3,734
BA.5.2.1BA.5.2.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Germany 13% 5,415 43,283
BA.5.1BA.5.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (89%), L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Greece 12% 9 72
BA.5.1.3BA.5.1.3 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D (88%), S371F (84%), S373P (89%), S375F (88%), T376A (88%), D405N, R408S, K417N, N440K (85%), L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, V289I, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Ukraine 12% 8 64
BA.5.2.1BA.5.2.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Ireland 12% 454 3,739
BA.5.2.1BA.5.2.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Italy 12% 919 7,704
BF.7BF.7 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, R346T, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Netherlands 12% 956 8,028
BA.5.2.1BA.5.2.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Sweden 12% 1,094 9,288
BA.5.2.1BA.5.2.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Spain 12% 611 5,230
BQ.1.1BQ.1.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, R346T, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, K444T, L452R, N460K, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron France 12% 3,118 26,746
BA.5.1BA.5.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (89%), L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Ireland 11% 428 3,739
BA.5.2BA.5.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Belgium 11% 799 7,025
BA.5.1BA.5.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (89%), L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Switzerland 11% 540 4,754
BA.5.2.1BA.5.2.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Estonia 11% 109 965
BA.5.1BA.5.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (89%), L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Sweden 11% 1,038 9,288
BA.5.2.1BA.5.2.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Denmark 11% 3,846 34,533
BA.5.2.1BA.5.2.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Poland 11% 227 2,040
BF.5BF.5 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (89%), L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K, A1020S
 Omicron Greece 11% 8 72
BA.5.2.1BA.5.2.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Slovenia 11% 320 2,887
BA.5.1BA.5.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (89%), L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Ukraine 11% 7 64
BA.5.1.23BA.5.1.23 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Ukraine 11% 7 64
BA.5.2.1BA.5.2.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Norway 11% 132 1,233
BA.5.1BA.5.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (89%), L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Denmark 11% 3,683 34,533
BA.5.2.1BA.5.2.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Czechia 11% 397 3,734
BA.5.2.1BA.5.2.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Portugal 11% 179 1,692
BF.7BF.7 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, R346T, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Denmark 11% 3,646 34,533
BA.5.1BA.5.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (89%), L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Belgium 11% 739 7,025
BA.5.2BA.5.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Liechtenstein 10% 17 166
BA.5.2.1BA.5.2.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Liechtenstein 10% 17 166
*Criteria: Above 10%, minimum of 50 samples per country.
Lineage WHO Label Country Percent Lineage Count Total Count
BA.4.6BA.4.6 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, R346T, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N658S, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Dominican Republic 65% 132 204
BA.5.2BA.5.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Panama 39% 30 77
BA.5.2.23BA.5.2.23 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N (86%), N440K, V445A, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, Y145H (87%), V213G, S255F, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Costa Rica 23% 190 821
BA.5.2.1BA.5.2.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Canada 22% 6,904 31,277
BA.5.2BA.5.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Guatemala 21% 20 97
BE.1.2BE.1.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, R346T, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (89%), L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Panama 18% 14 77
BA.5.2.1BA.5.2.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron United States 18% 26,305 145,432
BA.5.2.1BA.5.2.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Puerto Rico 18% 49 280
BA.5.1BA.5.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (89%), L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Mexico 15% 210 1,363
BA.5.2.1BA.5.2.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Mexico 15% 210 1,363
BA.5.1BA.5.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (89%), L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Guatemala 14% 14 97
BE.1.2.1BE.1.2.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, R346T, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, V445A, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Panama 13% 10 77
BA.5.2BA.5.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Canada 13% 4,024 31,277
BA.5.5BA.5.5 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (90%), L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, T76I, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Guatemala 12% 12 97
BA.5.2BA.5.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron United States 11% 16,549 145,432
BA.5.2.1BA.5.2.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Guatemala 11% 11 97
BE.1BE.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Guatemala 11% 11 97
BE.1BE.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Costa Rica 11% 88 821
BE.1.2.1BE.1.2.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, R346T, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, V445A, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Costa Rica 11% 88 821
BA.5.2.9BA.5.2.9 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Panama 10% 8 77
*Criteria: Above 10%, minimum of 50 samples per country.
Lineage WHO Label Country Percent Lineage Count Total Count
XBB.1XBB.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339H, R346T, L368I (85%), S371F (90%), S373P, S375F, T376A, D405N (90%), R408S (86%), K417N (87%), N440K, V445P (89%), G446S (90%), N460K, S477N, T478K, E484A, F486S, F490S, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, V83A, G142D, Y144- (83%), H146Q (86%), Q183E, V213E, G252V (81%), D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Bangladesh 68% 104 154
BA.5.2BA.5.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Thailand 46% 295 636
BA.5.2BA.5.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Mongolia 46% 44 95
BA.5.2BA.5.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Malaysia 43% 745 1,713
BA.5.2BA.5.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Indonesia 41% 1,700 4,122
BA.5.2BA.5.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Georgia 40% 61 152
BA.2.75BA.2.75 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339H, R346T (55%), S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, G446S, N460K, S477N, T478K, E484A, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24- (87%), P25- (87%), P26- (87%), A27S (88%), G142D (84%), K147E, W152R, F157L, I210V, V213G, G257S, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron India 40% 1,503 3,790
BA.5.2BA.5.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Pakistan 39% 69 175
BA.5.2BA.5.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron South Korea 39% 4,379 11,153
BA.5.2BA.5.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Brunei 39% 253 656
BA.5.2BA.5.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Cambodia 35% 38 108
BA.5.2BA.5.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Philippines 35% 179 515
BA.5.2BA.5.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Hong Kong 33% 302 913
BA.5.2BA.5.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Kazakhstan 31% 55 177
BF.5BF.5 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (89%), L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K, A1020S
 Omicron Japan 29% 8,646 30,323
BA.5.2BA.5.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Japan 28% 8,461 30,323
BA.5.2.1BA.5.2.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron South Korea 27% 3,022 11,153
XBB.1XBB.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339H, R346T, L368I (85%), S371F (90%), S373P, S375F, T376A, D405N (90%), R408S (86%), K417N (87%), N440K, V445P (89%), G446S (90%), N460K, S477N, T478K, E484A, F486S, F490S, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, V83A, G142D, Y144- (83%), H146Q (86%), Q183E, V213E, G252V (81%), D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Singapore 25% 856 3,407
BA.2.75BA.2.75 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339H, R346T (55%), S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, G446S, N460K, S477N, T478K, E484A, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24- (87%), P25- (87%), P26- (87%), A27S (88%), G142D (84%), K147E, W152R, F157L, I210V, V213G, G257S, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Singapore 21% 711 3,407
BA.5.2.27BA.5.2.27 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (80%), L452R (83%), S477N (84%), T478K (84%), E484A (84%), F486V (84%), Q498R (83%), N501Y (83%), Y505H (83%)
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Vietnam 20% 32 163
BA.5.2BA.5.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Israel 19% 1,760 9,312
BA.5.2.34BA.5.2.34 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, R346T, S371F, S373P, S375F, T376A, D405N, R408S (87%), K417N (88%), N440K (86%), L452R (88%), S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Cambodia 19% 20 108
BA.5.2.1BA.5.2.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Japan 18% 5,491 30,323
BM.1.1BM.1.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339H (74%), R346T (78%), S371F (66%), S373P (71%), S375F (70%), T376A (69%), D405N (71%), K417N (54%), N440K (61%), G446S (64%), N460K (66%), S477N (84%), T478K (83%), E484A (82%), F486S (82%), Q498R (85%), N501Y (85%), Y505H (84%)
Spike (non-RBD)T19I (89%), L24- (71%), P25- (71%), P26- (71%), A27S (74%), G142D (58%), I210V (58%), V213G (59%), G257S (65%), D614G, H655Y, N679K, P681H, N764K (84%), D796Y, Q954H, N969K
 Omicron Kuwait 17% 11 63
BA.5.2.6BA.5.2.6 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, R346T, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Indonesia 17% 712 4,122
BA.5.2.1BA.5.2.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Kazakhstan 17% 30 177
BA.5.2.1BA.5.2.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Vietnam 17% 27 163
BA.5.2BA.5.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Kuwait 16% 10 63
BA.2.75.2BA.2.75.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339H (79%), R346T (83%), S371F (75%), S373P (79%), S375F (78%), T376A (77%), D405N (81%), R408S (58%), K417N (58%), N440K (60%), G446S (60%), N460K (64%), S477N (81%), T478K (80%), E484A (78%), F486S (81%), Q498R (83%), N501Y (82%), Y505H (82%)
Spike (non-RBD)T19I (87%), L24- (75%), P25- (75%), P26- (75%), A27S (78%), F157L (50%), I210V (63%), V213G (65%), G257S (69%), D614G, H655Y, N679K, P681H, N764K (85%), D796Y, Q954H, N969K, D1199N
 Omicron Kuwait 14% 9 63
BA.5.2BA.5.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Singapore 14% 476 3,407
BA.5.2.1BA.5.2.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Georgia 13% 20 152
BA.5.2.1BA.5.2.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Brunei 13% 86 656
BA.2.3.20BA.2.3.20 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, K444R, N450D, L452M, N460K, S477N, T478K, E484R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, M153T, N164K, V213G, H245N, G257D, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Philippines 13% 66 515
BA.2.75BA.2.75 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339H, R346T (55%), S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, G446S, N460K, S477N, T478K, E484A, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24- (87%), P25- (87%), P26- (87%), A27S (88%), G142D (84%), K147E, W152R, F157L, I210V, V213G, G257S, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Brunei 13% 84 656
BQ.1.2BQ.1.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, K444T, L452R, N460K, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, I666V, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Mongolia 13% 12 95
BA.5.6BA.5.6 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (89%), L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Hong Kong 12% 109 913
BA.5.1BA.5.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (89%), L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Georgia 12% 18 152
BA.5.2.1BA.5.2.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Israel 11% 1,042 9,312
BN.1.3BN.1.3 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339H (69%), R346T (84%), K356T (87%), S371F (89%), S373P (88%), S375F (88%), T376A (88%), D405N, R408S (82%), K417N (80%), N440K (76%), G446S (73%), N460K (78%), S477N (87%), T478K (87%), E484A (87%), F490S (87%), Q498R (87%), N501Y (88%), Y505H (87%)
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D (66%), K147E (69%), W152R (78%), F157L (79%), I210V (75%), V213G (79%), G257S (61%), D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Vietnam 11% 18 163
BA.5.2.1BA.5.2.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Hong Kong 11% 99 913
BS.1.1BS.1.1 Mutations
ProteinMutations
Spike (RBD)G339D, R346T, K356T, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (81%), L452R (82%), N460K (83%), G476S (84%), S477N (84%), T478K (84%), E484A (84%), Q498R (84%), N501Y (84%), Y505H (84%)
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, Y144-, V213N (81%), ins213GEG (81%), G257V (85%), D614G, S640F, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 NA Vietnam 10% 17 163
BA.5.2BA.5.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Vietnam 10% 17 163
*Criteria: Above 10%, minimum of 50 samples per country.
Lineage WHO Label Country Percent Lineage Count Total Count
BA.5.2.1BA.5.2.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron New Zealand 22% 279 1,244
BA.5.2BA.5.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron New Zealand 21% 266 1,244
BA.5.2BA.5.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Australia 19% 3,050 15,973
BA.5.2.1BA.5.2.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Australia 16% 2,621 15,973
BA.2.75BA.2.75 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339H, R346T (55%), S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, G446S, N460K, S477N, T478K, E484A, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24- (87%), P25- (87%), P26- (87%), A27S (88%), G142D (84%), K147E, W152R, F157L, I210V, V213G, G257S, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Australia 12% 1,968 15,973
*Criteria: Above 10%, minimum of 50 samples per country.
Lineage WHO Label Country Percent Lineage Count Total Count
BA.4.6BA.4.6 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, R346T, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N658S, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Argentina 44% 48 109
BA.5.1BA.5.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (89%), L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Bonaire 37% 26 71
BA.5.3.1BA.5.3.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S (89%), K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Brazil 34% 348 1,024
BA.5.1BA.5.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (89%), L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Ecuador 26% 28 107
BA.5.2.1BA.5.2.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Trinidad And Tobago 21% 51 239
BA.5.2.1BA.5.2.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Brazil 21% 212 1,024
BA.5.2BA.5.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Ecuador 20% 21 107
BA.4.6BA.4.6 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, R346T, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N658S, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Chile 19% 404 2,141
BF.7.6BF.7.6 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, R346T, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Aruba 17% 17 102
BA.4.6BA.4.6 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, R346T, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N658S, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Peru 16% 297 1,807
BA.5.1BA.5.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (89%), L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Peru 16% 294 1,807
BA.4.6BA.4.6 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, R346T, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N658S, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Ecuador 16% 17 107
BF.7BF.7 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, R346T, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Curacao 15% 14 91
BF.31BF.31 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F (89%), S373P, S375F, T376A, D405N, R408S (89%), K417N (84%), L452R (90%), S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69- (90%), V70-, G142D (70%), V213G, D614G, H655Y, N679K, P681H, N764K (77%), D796Y, Q954H, N969K
 Omicron Chile 14% 306 2,141
BA.4.6BA.4.6 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, R346T, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N658S, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Trinidad And Tobago 14% 34 239
BA.5.1BA.5.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (89%), L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Trinidad And Tobago 13% 30 239
BF.10BF.10 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Trinidad And Tobago 13% 30 239
BA.5.1BA.5.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (89%), L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Curacao 12% 11 91
BA.5.1BA.5.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (89%), L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Brazil 12% 121 1,024
BA.5.2.1BA.5.2.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Chile 11% 245 2,141
BF.7.4.1BF.7.4.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, R346T, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Aruba 11% 11 102
*Criteria: Above 10%, minimum of 50 samples per country.
Lineage WHO Label Country Percent Lineage Count Total Count
BQ.1.1BQ.1.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, R346T, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, K444T, L452R, N460K, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Nigeria 54% 46 85
BA.5.3.1BA.5.3.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S (89%), K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron South Africa 38% 558 1,465
BA.5.1BA.5.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (89%), L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron France (Réunion Island) 21% 169 812
BQ.1BQ.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, K444T, L452R, N460K, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Nigeria 14% 12 85
BA.5BA.5 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S (89%), K417N, N440K (89%), L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron South Africa 14% 205 1,465
BA.5.2BA.5.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron France (Réunion Island) 12% 96 812
*Criteria: Above 10%, minimum of 50 samples per country.
Lineage WHO Label State Percent Lineage Count Total Count
BA.5.2.1BA.5.2.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Montana 39% 22 57
BA.5.2.1BA.5.2.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Oklahoma 30% 20 66
BA.5.2.1BA.5.2.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Oregon 27% 308 1,153
BA.5.2.1BA.5.2.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron North Dakota 26% 145 562
BA.5.2.1BA.5.2.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Vermont 25% 9 36
BA.5.2.1BA.5.2.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron South Dakota 23% 54 230
BA.5.2.1BA.5.2.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Alaska 23% 75 325
BA.5.2.1BA.5.2.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron West Virginia 23% 119 521
BA.5.2.1BA.5.2.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Kentucky 22% 135 603
BA.5.2.1BA.5.2.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron California 22% 5,722 25,705
BA.5.2BA.5.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron New Hampshire 22% 89 400
BA.5.2.1BA.5.2.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Ohio 22% 524 2,394
BA.5.2.1BA.5.2.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Wisconsin 21% 353 1,650
BA.5.2.1BA.5.2.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Washington 21% 1,281 6,013
BA.5.2.1BA.5.2.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron New Mexico 21% 153 724
BA.5.2.1BA.5.2.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Iowa 21% 226 1,088
BA.5.2.1BA.5.2.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Missouri 20% 225 1,098
BA.5.2.1BA.5.2.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Nebraska 20% 152 747
BA.5.2.1BA.5.2.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Colorado 20% 710 3,546
BA.5.2.1BA.5.2.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Nevada 19% 235 1,206
BA.5.2.1BA.5.2.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Kansas 19% 151 778
BA.5.2.1BA.5.2.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Wyoming 19% 50 258
BA.5.2.1BA.5.2.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Idaho 19% 99 519
BA.4.6BA.4.6 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, R346T, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N658S, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Mississippi 19% 53 280
BA.5.2.1BA.5.2.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron South Carolina 19% 198 1,050
BA.5.2.1BA.5.2.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Tennessee 19% 102 550
BA.5.2.1BA.5.2.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Utah 18% 522 2,829
BA.5.2.1BA.5.2.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Texas 18% 1,632 8,867
BA.5.2.1BA.5.2.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Maine 18% 22 121
BA.4.6BA.4.6 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, R346T, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N658S, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron North Carolina 18% 1,350 7,461
BA.5.2.1BA.5.2.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron District of Columbia 18% 135 751
BA.5.2.1BA.5.2.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Minnesota 18% 449 2,510
BA.5.2.1BA.5.2.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Virginia 18% 703 3,956
BA.5.2.1BA.5.2.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Illinois 17% 1,037 6,001
BA.5.2BA.5.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Arkansas 17% 51 296
BA.5.2.1BA.5.2.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Hawaii 17% 268 1,577
BA.5.2.1BA.5.2.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Arizona 17% 379 2,248
BA.5.2.1BA.5.2.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Michigan 16% 925 5,609
BA.5.2.1BA.5.2.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Delaware 16% 183 1,131
BA.5.2.1BA.5.2.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Connecticut 16% 493 3,060
BA.5.2BA.5.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Rhode Island 16% 191 1,192
BA.5.2.1BA.5.2.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron New Jersey 16% 1,146 7,229
BA.5.2.1BA.5.2.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Louisiana 16% 143 911
BA.5.2.1BA.5.2.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Maryland 16% 532 3,392
BA.5.2.1BA.5.2.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Pennsylvania 15% 765 4,975
BA.5.2.1BA.5.2.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Florida 15% 655 4,437
BA.5.2.1BA.5.2.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Indiana 15% 200 1,370
BA.5.2.1BA.5.2.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron New York 14% 2,499 17,342
BA.5.2BA.5.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Massachusetts 14% 533 3,810
BA.5.2BA.5.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Alabama 14% 36 260
BA.5.2.1BA.5.2.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Georgia 12% 266 2,165
*Criteria: Minimum of 20 samples per state.

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Lineage WHO Label Country 2-Week Period Change Previous Support Current Support
BQ.1BQ.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, K444T, L452R, N460K, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Turkey 2022-10-31 1% -> 32% (+30%) 18 / 1,236 52 / 163
BA.2.75BA.2.75 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339H, R346T (55%), S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, G446S, N460K, S477N, T478K, E484A, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24- (87%), P25- (87%), P26- (87%), A27S (88%), G142D (84%), K147E, W152R, F157L, I210V, V213G, G257S, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Liechtenstein 2022-10-31 12% -> 38% (+25%) 3 / 24 9 / 24
BA.5.2BA.5.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Bulgaria 2022-10-17 25% -> 50% (+25%) 25 / 100 19 / 38
BQ.1.1BQ.1.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, R346T, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, K444T, L452R, N460K, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Iceland 2022-10-31 10% -> 30% (+19%) 19 / 181 43 / 145
BA.5BA.5 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S (89%), K417N, N440K (89%), L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Italy 2022-11-14 4% -> 23% (+19%) 50 / 1,300 5 / 22
BQ.1.1BQ.1.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, R346T, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, K444T, L452R, N460K, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Ireland 2022-10-31 6% -> 20% (+14%) 20 / 325 34 / 167
BQ.1.1BQ.1.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, R346T, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, K444T, L452R, N460K, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Spain 2022-10-31 16% -> 29% (+14%) 179 / 1,137 110 / 376
BQ.1.1BQ.1.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, R346T, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, K444T, L452R, N460K, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Belgium 2022-10-31 7% -> 20% (+13%) 69 / 981 48 / 235
BA.5.1BA.5.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (89%), L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Russia 2022-10-31 5% -> 16% (+11%) 8 / 176 7 / 44
BF.7BF.7 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, R346T, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Norway 2022-10-31 5% -> 16% (+11%) 6 / 110 12 / 73
BQ.1.1BQ.1.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, R346T, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, K444T, L452R, N460K, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Portugal 2022-10-17 5% -> 15% (+10%) 16 / 351 34 / 233
BA.5.1.26BA.5.1.26 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, R346T, S371F (89%), S373P, S375F, T376A, D405N, R408S (87%), K417N, N440K (88%), L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Poland 2022-10-31 0% -> 10% (+10%) 1 / 304 6 / 59
BQ.1.1BQ.1.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, R346T, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, K444T, L452R, N460K, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron France 2022-10-17 14% -> 22% (+9%) 1,003 / 7,389 1,304 / 5,812
BQ.1.1BQ.1.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, R346T, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, K444T, L452R, N460K, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Croatia 2022-10-17 1% -> 9% (+8%) 5 / 472 24 / 271
BF.7BF.7 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, R346T, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Czechia 2022-10-17 11% -> 19% (+8%) 103 / 924 46 / 244
BE.1.1BE.1.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (85%), L452R, S477N, T478K, E484A, F486V, Q498R (90%), N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Denmark 2022-10-31 1% -> 9% (+7%) 90 / 6,900 488 / 5,609
BA.5.2.1BA.5.2.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Finland 2022-09-19 11% -> 18% (+7%) 24 / 228 41 / 229
BE.1.1BE.1.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (85%), L452R, S477N, T478K, E484A, F486V, Q498R (90%), N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron United Kingdom 2022-10-31 4% -> 11% (+7%) 345 / 9,519 326 / 3,080
BQ.1.1.15BQ.1.1.15 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D (71%), R346T (71%), S371F, S373P, S375F, T376A, D405N, R408S (60%), K417N, N440K, K444T, L452R, N460K, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24- (84%), P25- (84%), P26- (84%), A27S (84%), H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Luxembourg 2022-10-31 3% -> 10% (+7%) 34 / 1,176 47 / 494
CM.2CM.2 Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, K444R, N450D, L452M, N460K, S477N, T478K, E484R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, M153T, N164K, V213G, H245N, G257D, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 NA Austria 2022-10-03 3% -> 9% (+7%) 26 / 986 99 / 1,076
BQ.1.1BQ.1.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, R346T, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, K444T, L452R, N460K, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Netherlands 2022-10-17 4% -> 10% (+7%) 84 / 2,125 186 / 1,773
BA.5.2BA.5.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Slovakia 2022-09-19 20% -> 26% (+6%) 97 / 491 129 / 494
BA.2BA.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (85%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Germany 2022-10-31 1% -> 6% (+6%) 38 / 7,581 152 / 2,398
BQ.1.1BQ.1.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, R346T, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, K444T, L452R, N460K, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Slovenia 2022-10-17 1% -> 6% (+6%) 4 / 682 27 / 434
BQ.1.1BQ.1.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, R346T, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, K444T, L452R, N460K, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Sweden 2022-10-17 1% -> 7% (+5%) 23 / 2,063 129 / 1,976
BF.14BF.14 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, N450D, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Republic of Serbia 2022-09-19 5% -> 9% (+5%) 5 / 107 5 / 53
BQ.1.1BQ.1.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, R346T, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, K444T, L452R, N460K, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Switzerland 2022-10-17 3% -> 7% (+5%) 32 / 1,279 78 / 1,092
BF.7BF.7 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, R346T, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Estonia 2022-09-19 4% -> 7% (+4%) 13 / 351 28 / 376
BF.5BF.5 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (89%), L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K, A1020S
 Omicron Romania 2022-10-03 3% -> 6% (+3%) 4 / 153 9 / 153
*Criteria: >= +5% or >= 2x fold change between 2 week periods with >= 20 samples.
Lineage WHO Label Country 2-Week Period Change Previous Support Current Support
BA.5.5BA.5.5 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (90%), L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, T76I, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Guatemala 2022-09-19 8% -> 27% (+19%) 2 / 25 8 / 30
BA.5.2.23BA.5.2.23 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N (86%), N440K, V445A, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, Y145H (87%), V213G, S255F, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Costa Rica 2022-09-19 8% -> 26% (+18%) 15 / 200 57 / 221
BA.5.2.9BA.5.2.9 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Panama 2022-09-19 3% -> 19% (+16%) 1 / 35 6 / 31
BW.1BW.1 Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, K444T, L452R, N460K (90%), S477N, T478K, E484A, F486V (82%), Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, Y144- (68%), V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 NA Mexico 2022-10-03 3% -> 16% (+13%) 15 / 464 40 / 253
BQ.1.1BQ.1.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, R346T, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, K444T, L452R, N460K, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Dominican Republic 2022-10-17 2% -> 15% (+12%) 1 / 42 5 / 34
BF.11BF.11 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, R346T, S371F, S373P, S375F, T376A, D405N, R408S (90%), K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Puerto Rico 2022-10-31 5% -> 13% (+8%) 3 / 55 6 / 46
BQ.1BQ.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, K444T, L452R, N460K, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron United States 2022-10-17 2% -> 6% (+4%) 598 / 27,872 1,414 / 23,123
BQ.1BQ.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, K444T, L452R, N460K, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Canada 2022-10-17 1% -> 4% (+3%) 91 / 7,689 305 / 6,991
*Criteria: >= +5% or >= 2x fold change between 2 week periods with >= 20 samples.
Lineage WHO Label Country 2-Week Period Change Previous Support Current Support
XBB.1XBB.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339H, R346T, L368I (85%), S371F (90%), S373P, S375F, T376A, D405N (90%), R408S (86%), K417N (87%), N440K, V445P (89%), G446S (90%), N460K, S477N, T478K, E484A, F486S, F490S, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, V83A, G142D, Y144- (83%), H146Q (86%), Q183E, V213E, G252V (81%), D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Bangladesh 2022-09-19 25% -> 77% (+52%) 8 / 32 68 / 88
BN.1.3BN.1.3 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339H (69%), R346T (84%), K356T (87%), S371F (89%), S373P (88%), S375F (88%), T376A (88%), D405N, R408S (82%), K417N (80%), N440K (76%), G446S (73%), N460K (78%), S477N (87%), T478K (87%), E484A (87%), F490S (87%), Q498R (87%), N501Y (88%), Y505H (87%)
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D (66%), K147E (69%), W152R (78%), F157L (79%), I210V (75%), V213G (79%), G257S (61%), D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Vietnam 2022-10-03 6% -> 44% (+38%) 2 / 33 15 / 34
BA.5.2BA.5.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Pakistan 2022-09-19 32% -> 60% (+28%) 35 / 109 33 / 55
XBBXBB (Omicron) Mutations
ProteinMutations
Spike (RBD)G339H, R346T, L368I, S371F, S373P, S375F, T376A, D405N, R408S (89%), K417N (88%), N440K, V445P, G446S, N460K, S477N, T478K, E484A, F486S, F490S, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, V83A, G142D, Y144-, H146Q, Q183E, V213E, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Singapore 2022-10-31 12% -> 39% (+27%) 81 / 699 202 / 523
XBBXBB (Omicron) Mutations
ProteinMutations
Spike (RBD)G339H, R346T, L368I, S371F, S373P, S375F, T376A, D405N, R408S (89%), K417N (88%), N440K, V445P, G446S, N460K, S477N, T478K, E484A, F486S, F490S, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, V83A, G142D, Y144-, H146Q, Q183E, V213E, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Indonesia 2022-10-31 7% -> 25% (+17%) 87 / 1,177 82 / 334
BA.5.2BA.5.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Georgia 2022-10-03 32% -> 49% (+17%) 11 / 34 23 / 47
BA.2.75BA.2.75 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339H, R346T (55%), S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, G446S, N460K, S477N, T478K, E484A, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24- (87%), P25- (87%), P26- (87%), A27S (88%), G142D (84%), K147E, W152R, F157L, I210V, V213G, G257S, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Thailand 2022-10-17 11% -> 27% (+16%) 13 / 118 12 / 44
BA.2.3.20BA.2.3.20 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, K444R, N450D, L452M, N460K, S477N, T478K, E484R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, M153T, N164K, V213G, H245N, G257D, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Philippines 2022-09-19 6% -> 22% (+16%) 18 / 312 42 / 193
BQ.1.1BQ.1.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, R346T, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, K444T, L452R, N460K, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Hong Kong 2022-10-17 4% -> 20% (+16%) 7 / 171 6 / 30
XBBXBB (Omicron) Mutations
ProteinMutations
Spike (RBD)G339H, R346T, L368I, S371F, S373P, S375F, T376A, D405N, R408S (89%), K417N (88%), N440K, V445P, G446S, N460K, S477N, T478K, E484A, F486S, F490S, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, V83A, G142D, Y144-, H146Q, Q183E, V213E, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron India 2022-10-17 14% -> 26% (+12%) 106 / 778 44 / 171
BA.5.2BA.5.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Cambodia 2022-09-19 35% -> 47% (+12%) 14 / 40 16 / 34
BA.5.2BA.5.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron South Korea 2022-10-31 36% -> 47% (+10%) 888 / 2,438 34 / 73
BM.1.1BM.1.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339H (74%), R346T (78%), S371F (66%), S373P (71%), S375F (70%), T376A (69%), D405N (71%), K417N (54%), N440K (61%), G446S (64%), N460K (66%), S477N (84%), T478K (83%), E484A (82%), F486S (82%), Q498R (85%), N501Y (85%), Y505H (84%)
Spike (non-RBD)T19I (89%), L24- (71%), P25- (71%), P26- (71%), A27S (74%), G142D (58%), I210V (58%), V213G (59%), G257S (65%), D614G, H655Y, N679K, P681H, N764K (84%), D796Y, Q954H, N969K
 Omicron Kuwait 2022-10-03 12% -> 23% (+10%) 4 / 32 7 / 31
BA.2.75BA.2.75 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339H, R346T (55%), S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, G446S, N460K, S477N, T478K, E484A, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24- (87%), P25- (87%), P26- (87%), A27S (88%), G142D (84%), K147E, W152R, F157L, I210V, V213G, G257S, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Brunei 2022-10-17 15% -> 25% (+10%) 27 / 183 30 / 122
BA.2BA.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (85%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Malaysia 2022-10-31 1% -> 10% (+9%) 3 / 248 25 / 247
BQ.1.1BQ.1.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, R346T, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, K444T, L452R, N460K, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Israel 2022-10-31 11% -> 17% (+6%) 230 / 2,094 166 / 954
*Criteria: >= +5% or >= 2x fold change between 2 week periods with >= 20 samples.
Lineage WHO Label Country 2-Week Period Change Previous Support Current Support
BA.2.75BA.2.75 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339H, R346T (55%), S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, G446S, N460K, S477N, T478K, E484A, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24- (87%), P25- (87%), P26- (87%), A27S (88%), G142D (84%), K147E, W152R, F157L, I210V, V213G, G257S, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Australia 2022-11-14 26% -> 42% (+16%) 643 / 2,450 14 / 33
BA.5.6BA.5.6 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (89%), L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron New Zealand 2022-10-03 4% -> 7% (+4%) 15 / 415 5 / 67
*Criteria: >= +5% or >= 2x fold change between 2 week periods with >= 20 samples.
Lineage WHO Label Country 2-Week Period Change Previous Support Current Support
BA.5.1.25BA.5.1.25 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S (83%), K417N, N440K (89%), L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Peru 2022-10-17 8% -> 77% (+69%) 15 / 194 73 / 95
BA.5.3.1BA.5.3.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S (89%), K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Brazil 2022-10-03 11% -> 55% (+44%) 13 / 120 79 / 143
BA.5.1BA.5.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (89%), L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Argentina 2022-10-03 4% -> 24% (+20%) 1 / 24 5 / 21
BF.7BF.7 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, R346T, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Curacao 2022-09-19 10% -> 24% (+14%) 3 / 30 6 / 25
BA.5.2.1BA.5.2.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Trinidad And Tobago 2022-10-17 29% -> 39% (+11%) 14 / 49 13 / 33
BF.7BF.7 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, R346T, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Aruba 2022-10-17 5% -> 16% (+10%) 2 / 37 5 / 32
BF.31.1BF.31.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N (89%), L452R, S477N, T478K, E484A, F486V, Q498R (89%), N501Y (89%), Y505H (89%)
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D (65%), V213G, S247N, Y248-, D614G, H655Y, N679K, P681H, A701V, N764K, D796Y, Q954H, N969K
 Omicron Chile 2022-10-31 12% -> 18% (+6%) 66 / 538 13 / 73
*Criteria: >= +5% or >= 2x fold change between 2 week periods with >= 20 samples.
Lineage WHO Label Country 2-Week Period Change Previous Support Current Support
BQ.1.1BQ.1.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, R346T, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, K444T, L452R, N460K, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron France (Réunion Island) 2022-10-03 2% -> 19% (+17%) 3 / 125 24 / 125
BA.5.3.5BA.5.3.5 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, R346T, S371F, S373P, S375F, T376A, D405N, R408S (70%), K417N (90%), N440K (88%), L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I (83%), L24- (84%), P25- (84%), P26- (84%), A27S (84%), H69- (84%), V70- (84%), G142D (75%), V213G (81%), D614G, H655Y, N679K, P681H, N764K (90%), D796Y, Q954H, N969K
 Omicron South Africa 2022-10-31 6% -> 20% (+14%) 24 / 384 11 / 55
BQ.1BQ.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, K444T, L452R, N460K, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Nigeria 2022-09-19 12% -> 19% (+7%) 5 / 42 5 / 27
*Criteria: >= +5% or >= 2x fold change between 2 week periods with >= 20 samples.
Lineage WHO Label State 2-Week Period Change Previous Support Current Support
BQ.1.1BQ.1.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, R346T, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, K444T, L452R, N460K, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Idaho 2022-10-31 4% -> 49% (+45%) 4 / 94 30 / 61
BA.5.2BA.5.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Wyoming 2022-10-31 16% -> 48% (+32%) 8 / 50 10 / 21
BF.10BF.10 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Arkansas 2022-10-03 2% -> 31% (+28%) 2 / 94 11 / 36
BQ.1.12BQ.1.12 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, K444T, L452R, N460K, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron New Mexico 2022-10-31 6% -> 30% (+24%) 11 / 196 20 / 67
BA.5.2.1BA.5.2.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Kentucky 2022-10-03 20% -> 38% (+18%) 33 / 166 35 / 92
BQ.1.1BQ.1.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, R346T, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, K444T, L452R, N460K, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Colorado 2022-10-31 5% -> 23% (+18%) 23 / 437 10 / 43
BF.10BF.10 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Louisiana 2022-10-31 7% -> 22% (+15%) 7 / 105 17 / 78
BQ.1.1BQ.1.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, R346T, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, K444T, L452R, N460K, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Nevada 2022-10-31 6% -> 21% (+14%) 24 / 375 27 / 131
BF.5BF.5 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (89%), L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K, A1020S
 Omicron Maine 2022-09-19 5% -> 19% (+14%) 2 / 44 11 / 59
BQ.1BQ.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, K444T, L452R, N460K, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Rhode Island 2022-10-17 1% -> 15% (+14%) 3 / 273 8 / 53
BA.4.6BA.4.6 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, R346T, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N658S, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Alaska 2022-10-17 12% -> 25% (+13%) 5 / 42 6 / 24
BA.5.2BA.5.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron New Hampshire 2022-09-19 17% -> 28% (+12%) 26 / 157 34 / 120
BA.5.2.1BA.5.2.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron South Dakota 2022-09-19 20% -> 31% (+11%) 21 / 103 14 / 45
BF.10BF.10 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Nebraska 2022-10-31 1% -> 11% (+10%) 1 / 157 8 / 72
BA.5.2BA.5.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Alabama 2022-10-03 19% -> 29% (+10%) 13 / 68 10 / 34
BA.5.2.3BA.5.2.3 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron North Dakota 2022-09-19 1% -> 11% (+10%) 2 / 171 19 / 174
BA.5.2BA.5.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Tennessee 2022-10-03 8% -> 18% (+10%) 15 / 177 12 / 66
BA.4.6BA.4.6 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, R346T, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N658S, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Mississippi 2022-09-19 15% -> 24% (+9%) 23 / 151 28 / 115
BA.5.2BA.5.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron West Virginia 2022-10-03 11% -> 20% (+9%) 14 / 132 14 / 71
BQ.1.1BQ.1.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, R346T, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, K444T, L452R, N460K, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron District of Columbia 2022-10-03 1% -> 10% (+9%) 2 / 164 18 / 176
BQ.1.1BQ.1.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, R346T, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, K444T, L452R, N460K, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron New York 2022-10-31 10% -> 19% (+9%) 304 / 3,051 234 / 1,244
BF.7BF.7 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, R346T, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Oregon 2022-10-31 1% -> 10% (+9%) 1 / 94 5 / 51
BQ.1BQ.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, K444T, L452R, N460K, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron New Jersey 2022-10-17 9% -> 17% (+9%) 124 / 1,446 167 / 969
BA.5.1.6BA.5.1.6 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Arizona 2022-10-31 14% -> 23% (+9%) 71 / 495 68 / 297
BQ.1.1BQ.1.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, R346T, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, K444T, L452R, N460K, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Maryland 2022-10-31 10% -> 17% (+7%) 74 / 733 62 / 359
BQ.1BQ.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, K444T, L452R, N460K, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Ohio 2022-10-31 3% -> 10% (+7%) 14 / 443 9 / 89
BQ.1.1BQ.1.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, R346T, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, K444T, L452R, N460K, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Virginia 2022-10-31 4% -> 11% (+7%) 26 / 622 20 / 183
BA.5.2.1BA.5.2.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron South Carolina 2022-10-17 14% -> 20% (+7%) 17 / 124 40 / 196
BQ.1.1BQ.1.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, R346T, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, K444T, L452R, N460K, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Pennsylvania 2022-10-17 1% -> 8% (+6%) 11 / 976 62 / 818
BQ.1.1BQ.1.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, R346T, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, K444T, L452R, N460K, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Florida 2022-10-17 2% -> 9% (+6%) 15 / 652 43 / 492
BQ.1BQ.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, K444T, L452R, N460K, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Georgia 2022-10-17 1% -> 8% (+6%) 5 / 335 29 / 374
BA.5.2.1BA.5.2.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Iowa 2022-10-17 18% -> 24% (+6%) 37 / 205 63 / 261
BF.26BF.26 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Kansas 2022-09-19 3% -> 9% (+6%) 7 / 275 17 / 199
BA.5.2.6BA.5.2.6 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, R346T, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Massachusetts 2022-10-17 1% -> 7% (+6%) 11 / 929 40 / 565
BQ.1BQ.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, K444T, L452R, N460K, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Wisconsin 2022-10-31 2% -> 8% (+6%) 8 / 353 5 / 62
BQ.1.1BQ.1.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, R346T, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, K444T, L452R, N460K, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Indiana 2022-10-17 0% -> 6% (+6%) 1 / 266 17 / 277
BQ.1.1BQ.1.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, R346T, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, K444T, L452R, N460K, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Texas 2022-10-31 6% -> 12% (+6%) 56 / 893 32 / 268
BQ.1.1BQ.1.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, R346T, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, K444T, L452R, N460K, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Connecticut 2022-10-17 2% -> 7% (+5%) 14 / 682 26 / 360
XBBXBB (Omicron) Mutations
ProteinMutations
Spike (RBD)G339H, R346T, L368I, S371F, S373P, S375F, T376A, D405N, R408S (89%), K417N (88%), N440K, V445P, G446S, N460K, S477N, T478K, E484A, F486S, F490S, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, V83A, G142D, Y144-, H146Q, Q183E, V213E, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Minnesota 2022-10-31 1% -> 5% (+5%) 3 / 492 7 / 130
BQ.1BQ.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, K444T, L452R, N460K, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Delaware 2022-10-17 1% -> 6% (+4%) 4 / 270 6 / 101
BQ.1.1BQ.1.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, R346T, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, K444T, L452R, N460K, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron California 2022-10-17 1% -> 6% (+4%) 60 / 4,477 186 / 3,281
BQ.1BQ.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, K444T, L452R, N460K, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Washington 2022-10-31 3% -> 7% (+4%) 26 / 970 32 / 461
BQ.1BQ.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, K444T, L452R, N460K, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Hawaii 2022-10-17 4% -> 8% (+4%) 14 / 382 28 / 363
BQ.1BQ.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, K444T, L452R, N460K, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Illinois 2022-10-17 1% -> 5% (+4%) 8 / 1,075 59 / 1,259
BQ.1.1BQ.1.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, R346T, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, K444T, L452R, N460K, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron North Carolina 2022-10-17 1% -> 5% (+4%) 16 / 1,235 51 / 1,031
BE.1.1BE.1.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (85%), L452R, S477N, T478K, E484A, F486V, Q498R (90%), N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Utah 2022-10-17 2% -> 6% (+3%) 8 / 328 48 / 848
BF.7BF.7 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, R346T, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Michigan 2022-10-17 3% -> 6% (+3%) 35 / 1,227 60 / 1,051
BQ.1BQ.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, K444T, L452R, N460K, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
 Omicron Missouri 2022-10-17 1% -> 3% (+3%) 1 / 156 7 / 208
*Criteria: >= +5% or >= 2x fold change between 2-week periods with >= 20 samples.

Data Timeline

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Dashboard Timeline

November 02, 2022
06:00PM

New emerging mutations graph and improved performance

Added plot to track emerging mutations. Significantly sped up common plots with an application-level cache
August 02, 2022
07:00PM

Cache loading updated

Modified cache loading logic to avoid incomplete loading of cache
July 26, 2022
08:00PM

QC pipeline updated

Began filtering out genomes <= 25kb in length and >30% undetermined bases, and began re-calling undetermined lineages
January 07, 2022
04:30PM

Top/emerging variant graphs updated

Added overlays and country-specific information to variant graphs
November 27, 2021
01:30PM

WHO Labels Updated

Added Omicron WHO variant
November 18, 2021
04:30PM

Dashboard UI/graphs updated

Added WHO labels to lineages
April 16, 2021
08:50PM

Dashboard UI/graphs updated

Added emerging lineages tracking and top lineages tracking per US state to home page
April 16, 2021
08:00PM

Dashboard backend pipeline overhauled

Overhauled backend pipeline to automatically download and QC data from GISAID daily
April 05, 2021
03:30PM

Dashboard UI/graphs updated

Added top and emerging lineage maps and graphs. Overhauled home page
March 23, 2021
06:00PM

Dashboard performance overhauled

Added caching and refactored all graphs for performance before public release
November 13, 2020
04:00PM

Dashboard UI/graphs updated

Broad-scale update across the entire dashboard to prepare for its launch onto the world wide web!
June 15, 2020
12:00AM

Dashboard graphs upgraded

Migrated dashboard graphs from Plotly to ECharts
June 04, 2020
08:06PM

Dashboard data source changed

Upgraded dashboard to use a database vs flat files. 3x reduction in load time
June 02, 2020
12:18PM

Dashboard UI upgraded

Overhauled dashboard user interface to use bs4dash
May 26, 2020
12:00AM

Variant tracking expanded

Began tracking variants in genes ORF1a and ORF1b
May 11, 2020
12:00AM

Variant tracking expanded

Began tracking variants in genes E, M, N, ORF3a, ORF7a, ORF8, and ORF10
April 27, 2020
12:00AM

Phylogenetic analysis added

Added tab containing viral genome evolutionary relationships
April 03, 2020
12:00AM

Automated QC pipeline created

Cleans up metadata fields such as age, collection date, gender, etc
April 02, 2020
10:36AM

First version of dashboard created

Created first version with shinydashboard. Data is ingested from flat files
March 31, 2020
12:00AM

Patient metadata tracking started

Began downloading patient metadata for all genomes
January 10, 2020
12:00AM

First data downloaded

Began downloading genomes from GISAID and subsequent variant calling
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