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Welcome to the Regeneron COVID-19 Dashboard

This dashboard contains aggregated information on SARS-CoV-2 (hCoV-19) genomes and associated patient metadata, gathered in partnership with the GISAID initiative.

The goal of the dashboard is to enable scientists to understand the evolution of this emerging coronavirus by monitoring and displaying pertinent information. For example, the dashboard displays the novel mutations in SARS-CoV-2 (hCoV-19) genomes across time and geographical location, which facilitates the identification of a mutation that may increase transmission or virulence.

In addition, there is de-identified patient demographic information such as country of origin, patient status, and age, which provides further insights into the populations most susceptible to the virus.

11,401,089

SARS-CoV-2 (hCoV-19) genomes

June 24, 2022

06:34 PM ET

Last data update

Top Lineages Per Country (Past 12 Weeks)

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Lineage WHO Label Country Percent Lineage Count Total Count
BA.2BA.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Turkey 88% 2,191 2,503
BA.2BA.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Russia 87% 312 358
BA.2BA.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Republic of Serbia 86% 315 368
BA.2BA.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Liechtenstein 79% 98 124
BA.2BA.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Croatia 77% 1,540 2,009
BA.2BA.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Slovenia 76% 2,112 2,791
UnassignedUnassigned Mutations
ProteinMutations
Spike (RBD)N501Y (62%)
Spike (non-RBD)D614G (89%), P681H (63%)
NA Austria 75% 18,992 25,285
BA.2BA.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Romania 75% 370 493
BA.2BA.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron France 74% 25,564 34,373
BA.2BA.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Sweden 74% 4,079 5,499
BA.2BA.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Luxembourg 73% 4,176 5,723
BA.2BA.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Switzerland 72% 2,958 4,086
BA.2BA.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Slovakia 72% 2,738 3,814
BA.2BA.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Germany 70% 68,943 98,735
BA.2BA.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Belgium 70% 8,904 12,762
BA.2BA.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Estonia 68% 1,045 1,527
BA.2BA.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Greece 68% 306 449
BA.2BA.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron United Kingdom 68% 68,330 100,501
BA.2BA.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Norway 68% 2,899 4,289
BA.2BA.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Italy 67% 6,929 10,294
BA.2BA.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Ireland 66% 4,153 6,287
BA.2BA.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Finland 64% 1,045 1,634
BA.2BA.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Denmark 63% 35,110 55,487
BA.2BA.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Spain 61% 8,444 13,762
BA.2BA.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Netherlands 58% 5,744 9,877
BA.2BA.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Lithuania 52% 1,086 2,076
BA.2.9BA.2.9 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Poland 51% 589 1,146
BA.2BA.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Portugal 45% 2,291 5,037
BA.2.9BA.2.9 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Czechia 45% 2,188 4,828
BA.2BA.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Czechia 44% 2,140 4,828
BA.2BA.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Poland 41% 471 1,146
BA.5BA.5 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Portugal 36% 1,819 5,037
BA.2.9BA.2.9 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Lithuania 36% 749 2,076
BA.2.9BA.2.9 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Finland 21% 348 1,634
BA.2.9BA.2.9 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Estonia 20% 313 1,527
BA.2.9BA.2.9 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Slovakia 20% 778 3,814
BA.2.9BA.2.9 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Denmark 20% 10,862 55,487
BA.2.9BA.2.9 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Norway 18% 770 4,289
BA.2.9BA.2.9 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Romania 18% 87 493
BA.2.9BA.2.9 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Spain 16% 2,139 13,762
BA.2.9BA.2.9 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Germany 15% 14,881 98,735
BA.2BA.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Austria 14% 3,629 25,285
BA.2.9BA.2.9 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Croatia 14% 287 2,009
BA.2.9BA.2.9 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Sweden 13% 731 5,499
BA.2.9BA.2.9 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Netherlands 13% 1,288 9,877
BA.2.9BA.2.9 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Greece 11% 51 449
BA.2.9BA.2.9 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Italy 10% 1,057 10,294
BA.2.9BA.2.9 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Slovenia 10% 281 2,791
*Criteria: Above 10%, minimum of 50 samples per country.
Lineage WHO Label Country Percent Lineage Count Total Count
UnassignedUnassigned Mutations
ProteinMutations
Spike (RBD)N501Y (62%)
Spike (non-RBD)D614G (89%), P681H (63%)
NA Cuba 100% 98 98
BA.2BA.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Martinique 58% 118 205
BA.2BA.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Sint Maarten 55% 82 148
BA.2BA.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron U.S. Virgin Islands 53% 32 60
BA.2BA.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Puerto Rico 52% 428 826
BA.2.9BA.2.9 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Guadeloupe 51% 32 63
BA.2BA.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Guadeloupe 44% 28 63
BA.2BA.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Canada 44% 16,223 37,009
BA.2BA.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Panama 41% 140 341
BA.2.12.1BA.2.12.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452Q, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, S704L, N764K, D796Y, Q954H, N969K
Omicron United States 39% 113,024 293,342
BA.2BA.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron United States 35% 102,577 293,342
BA.2.9BA.2.9 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Panama 34% 116 341
BA.1.1BA.1.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, R346K, S371L (87%), S373P (88%), S375F (88%), K417N (69%), N440K (74%), G446S (75%), S477N, T478K, E484A, Q493R, G496S (89%), Q498R (88%), N501Y (89%), Y505H (89%)
Spike (non-RBD)A67V, H69-, V70-, T95I, G142D, V143-, Y144-, Y145-, N211- (87%), L212I (87%), ins214EPE (78%), T547K, D614G, H655Y, N679K, P681H, N764K, D796Y, N856K, Q954H, N969K, L981F
Omicron Guatemala 34% 55 162
BA.2.9BA.2.9 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Costa Rica 32% 315 977
BA.2BA.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Costa Rica 32% 310 977
BA.2BA.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Mexico 31% 922 2,998
BA.2.12.1BA.2.12.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452Q, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, S704L, N764K, D796Y, Q954H, N969K
Omicron Puerto Rico 28% 228 826
BA.2BA.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Guatemala 27% 44 162
BA.5BA.5 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Martinique 27% 55 205
BA.2.3BA.2.3 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (86%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron U.S. Virgin Islands 23% 14 60
BA.2.12.1BA.2.12.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452Q, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, S704L, N764K, D796Y, Q954H, N969K
Omicron Mexico 21% 630 2,998
BA.2.9BA.2.9 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Mexico 20% 612 2,998
BA.2.12.1BA.2.12.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452Q, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, S704L, N764K, D796Y, Q954H, N969K
Omicron Sint Maarten 20% 30 148
BA.2.12.1BA.2.12.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452Q, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, S704L, N764K, D796Y, Q954H, N969K
Omicron Canada 19% 6,986 37,009
BA.2.3BA.2.3 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (86%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Canada 19% 6,902 37,009
BA.2.3BA.2.3 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (86%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Costa Rica 18% 173 977
BA.2.9BA.2.9 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Sint Maarten 16% 24 148
BA.2.3BA.2.3 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (86%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Guatemala 15% 25 162
BA.2.9BA.2.9 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron U.S. Virgin Islands 13% 8 60
BA.2.9BA.2.9 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Martinique 10% 21 205
*Criteria: Above 10%, minimum of 50 samples per country.
Lineage WHO Label Country Percent Lineage Count Total Count
BA.2BA.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Kazakhstan 93% 64 69
BA.2.2BA.2.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K, I1221T
Omicron China 92% 49 53
BA.2.3BA.2.3 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (86%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Brunei 87% 106 122
BA.2BA.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Nepal 86% 86 100
BA.2BA.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron India 78% 4,447 5,682
BA.2BA.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Malaysia 66% 1,385 2,087
BA.2BA.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Pakistan 65% 106 164
UnassignedUnassigned Mutations
ProteinMutations
Spike (RBD)N501Y (62%)
Spike (non-RBD)D614G (89%), P681H (63%)
NA Iran 63% 210 334
BA.2BA.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Israel 53% 13,275 25,048
BA.2BA.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Thailand 50% 1,351 2,710
BA.2BA.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Singapore 49% 1,581 3,254
BA.2.2BA.2.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K, I1221T
Omicron Hong Kong 46% 576 1,247
BA.2.3BA.2.3 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (86%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Cambodia 45% 53 119
UnassignedUnassigned Mutations
ProteinMutations
Spike (RBD)N501Y (62%)
Spike (non-RBD)D614G (89%), P681H (63%)
NA South Korea 42% 5,381 12,806
BA.2BA.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Laos 39% 32 83
BA.2.3BA.2.3 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (86%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Laos 37% 31 83
BA.2BA.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Indonesia 37% 311 839
BA.2.3BA.2.3 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (86%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Philippines 35% 106 303
BA.2BA.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Philippines 35% 106 303
BA.2.3BA.2.3 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (86%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron South Korea 33% 4,219 12,806
BA.2BA.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Cambodia 33% 39 119
BA.2BA.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Iran 32% 108 334
BA.2.3BA.2.3 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (86%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Vietnam 31% 177 562
BA.2.3.2BA.2.3.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (82%), S477N (88%), T478K (88%), E484A (88%), Q493R (88%), Q498R (88%), N501Y (88%), Y505H (88%)
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Vietnam 31% 173 562
BA.2.3BA.2.3 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (86%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Indonesia 29% 241 839
BA.2BA.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Vietnam 28% 159 562
BA.2BA.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Hong Kong 26% 324 1,247
BA.2.9BA.2.9 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Thailand 25% 665 2,710
BA.2.3BA.2.3 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (86%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Japan 22% 7,033 31,737
BA.2BA.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron South Korea 21% 2,700 12,806
BA.2.3.2BA.2.3.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (82%), S477N (88%), T478K (88%), E484A (88%), Q493R (88%), Q498R (88%), N501Y (88%), Y505H (88%)
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Laos 19% 16 83
BA.2.3BA.2.3 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (86%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Malaysia 19% 397 2,087
BA.2BA.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Japan 18% 5,698 31,737
BA.2.3.1BA.2.3.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, Q677E, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Japan 16% 4,940 31,737
BA.5BA.5 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Pakistan 15% 24 164
BA.5BA.5 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Indonesia 14% 120 839
BA.5BA.5 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Israel 14% 3,434 25,048
BA.2.3BA.2.3 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (86%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Singapore 13% 427 3,254
BA.2.12.1BA.2.12.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452Q, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, S704L, N764K, D796Y, Q954H, N969K
Omicron Philippines 13% 38 303
BA.2.10BA.2.10 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S (89%), K417N, N440K (81%), S477N, T478K, E484A, Q493R (85%), Q498R (87%), N501Y (88%), Y505H (89%)
Spike (non-RBD)T19I, L24- (87%), P25- (87%), P26- (87%), A27S (87%), G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Cambodia 12% 14 119
BA.5BA.5 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Singapore 12% 382 3,254
BA.2.12.1BA.2.12.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452Q, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, S704L, N764K, D796Y, Q954H, N969K
Omicron Hong Kong 11% 140 1,247
BA.2.29BA.2.29 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Japan 11% 3,518 31,737
BA.2.24BA.2.24 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339N, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Japan 10% 3,271 31,737
*Criteria: Above 10%, minimum of 50 samples per country.
Lineage WHO Label Country Percent Lineage Count Total Count
BA.2BA.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Australia 67% 15,566 23,121
BA.2BA.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron New Zealand 60% 1,417 2,370
BA.2.3BA.2.3 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (86%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Solomon Islands 51% 66 130
BA.2.3.3BA.2.3.3 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Solomon Islands 43% 56 130
BA.2.10BA.2.10 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S (89%), K417N, N440K (81%), S477N, T478K, E484A, Q493R (85%), Q498R (87%), N501Y (88%), Y505H (89%)
Spike (non-RBD)T19I, L24- (87%), P25- (87%), P26- (87%), A27S (87%), G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron New Zealand 28% 673 2,370
*Criteria: Above 10%, minimum of 50 samples per country.
Lineage WHO Label Country Percent Lineage Count Total Count
BA.2BA.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Brazil 66% 4,131 6,219
BA.2BA.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Colombia 55% 454 830
BA.2BA.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Paraguay 49% 68 139
BA.2BA.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Peru 46% 833 1,828
BA.2BA.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Bonaire 45% 61 136
BA.2.9BA.2.9 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Trinidad And Tobago 44% 110 251
BA.2BA.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Trinidad And Tobago 42% 105 251
BA.2BA.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Ecuador 41% 88 215
BA.2BA.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Chile 41% 1,116 2,731
BA.2BA.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Argentina 40% 106 266
BA.2.30BA.2.30 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Curacao 37% 94 257
BA.2BA.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Curacao 34% 88 257
BA.2.12.1BA.2.12.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452Q, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, S704L, N764K, D796Y, Q954H, N969K
Omicron Aruba 27% 31 115
BA.2.12.1BA.2.12.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452Q, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, S704L, N764K, D796Y, Q954H, N969K
Omicron Peru 24% 430 1,828
BA.2.3BA.2.3 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (86%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Argentina 22% 58 266
BA.1.1BA.1.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, R346K, S371L (87%), S373P (88%), S375F (88%), K417N (69%), N440K (74%), G446S (75%), S477N, T478K, E484A, Q493R, G496S (89%), Q498R (88%), N501Y (89%), Y505H (89%)
Spike (non-RBD)A67V, H69-, V70-, T95I, G142D, V143-, Y144-, Y145-, N211- (87%), L212I (87%), ins214EPE (78%), T547K, D614G, H655Y, N679K, P681H, N764K, D796Y, N856K, Q954H, N969K, L981F
Omicron Paraguay 21% 29 139
BA.2.12.1BA.2.12.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452Q, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, S704L, N764K, D796Y, Q954H, N969K
Omicron Ecuador 20% 44 215
BA.2BA.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Aruba 19% 22 115
BA.1.1BA.1.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, R346K, S371L (87%), S373P (88%), S375F (88%), K417N (69%), N440K (74%), G446S (75%), S477N, T478K, E484A, Q493R, G496S (89%), Q498R (88%), N501Y (89%), Y505H (89%)
Spike (non-RBD)A67V, H69-, V70-, T95I, G142D, V143-, Y144-, Y145-, N211- (87%), L212I (87%), ins214EPE (78%), T547K, D614G, H655Y, N679K, P681H, N764K, D796Y, N856K, Q954H, N969K, L981F
Omicron Chile 18% 500 2,731
BA.1.1BA.1.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, R346K, S371L (87%), S373P (88%), S375F (88%), K417N (69%), N440K (74%), G446S (75%), S477N, T478K, E484A, Q493R, G496S (89%), Q498R (88%), N501Y (89%), Y505H (89%)
Spike (non-RBD)A67V, H69-, V70-, T95I, G142D, V143-, Y144-, Y145-, N211- (87%), L212I (87%), ins214EPE (78%), T547K, D614G, H655Y, N679K, P681H, N764K, D796Y, N856K, Q954H, N969K, L981F
Omicron Argentina 17% 45 266
BA.2.30BA.2.30 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Aruba 17% 19 115
BA.1.1BA.1.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, R346K, S371L (87%), S373P (88%), S375F (88%), K417N (69%), N440K (74%), G446S (75%), S477N, T478K, E484A, Q493R, G496S (89%), Q498R (88%), N501Y (89%), Y505H (89%)
Spike (non-RBD)A67V, H69-, V70-, T95I, G142D, V143-, Y144-, Y145-, N211- (87%), L212I (87%), ins214EPE (78%), T547K, D614G, H655Y, N679K, P681H, N764K, D796Y, N856K, Q954H, N969K, L981F
Omicron Ecuador 15% 32 215
UnassignedUnassigned Mutations
ProteinMutations
Spike (RBD)N501Y (62%)
Spike (non-RBD)D614G (89%), P681H (63%)
NA Colombia 12% 101 830
BA.2.9BA.2.9 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Argentina 12% 32 266
BA.5BA.5 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Aruba 11% 13 115
BA.2.3BA.2.3 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (86%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Chile 11% 305 2,731
*Criteria: Above 10%, minimum of 50 samples per country.
Lineage WHO Label Country Percent Lineage Count Total Count
BA.2BA.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron France (Réunion Island) 92% 526 573
BA.2BA.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Morocco 67% 39 58
BA.2BA.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Mauritius 64% 259 404
BA.4BA.4 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)V3G (55%), T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron South Africa 56% 2,417 4,326
BA.5BA.5 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Eswatini 55% 62 112
BA.2BA.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Ghana 52% 38 73
BA.2BA.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Botswana 41% 64 155
BA.2BA.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Kenya 33% 41 125
BA.2BA.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Eswatini 26% 29 112
BA.4BA.4 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)V3G (55%), T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Ghana 25% 18 73
BA.4BA.4 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)V3G (55%), T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Botswana 25% 38 155
BA.2.23BA.2.23 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Botswana 24% 37 155
UnassignedUnassigned Mutations
ProteinMutations
Spike (RBD)N501Y (62%)
Spike (non-RBD)D614G (89%), P681H (63%)
NA Ghana 22% 16 73
BA.2BA.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron South Africa 21% 918 4,326
BA.2.12.1BA.2.12.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452Q, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, S704L, N764K, D796Y, Q954H, N969K
Omicron Kenya 20% 25 125
BA.5BA.5 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron South Africa 19% 814 4,326
BA.2.31BA.2.31 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S (70%), K417N (71%), N440K (56%), S477N (87%), T478K (87%), E484A (88%), Q493R (87%), Q498R (88%), N501Y (89%), Y505H (88%)
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Kenya 18% 23 125
BA.4BA.4 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)V3G (55%), T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Eswatini 15% 17 112
BA.5BA.5 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Kenya 13% 16 125
UnassignedUnassigned Mutations
ProteinMutations
Spike (RBD)N501Y (62%)
Spike (non-RBD)D614G (89%), P681H (63%)
NA Mauritius 12% 47 404
BA.2.10BA.2.10 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S (89%), K417N, N440K (81%), S477N, T478K, E484A, Q493R (85%), Q498R (87%), N501Y (88%), Y505H (89%)
Spike (non-RBD)T19I, L24- (87%), P25- (87%), P26- (87%), A27S (87%), G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Mauritius 11% 46 404
*Criteria: Above 10%, minimum of 50 samples per country.
Lineage WHO Label State Percent Lineage Count Total Count
BA.2.12.1BA.2.12.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452Q, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, S704L, N764K, D796Y, Q954H, N969K
Omicron New York 54% 22,991 42,389
BA.2.12.1BA.2.12.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452Q, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, S704L, N764K, D796Y, Q954H, N969K
Omicron South Carolina 52% 760 1,468
BA.2.12.1BA.2.12.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452Q, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, S704L, N764K, D796Y, Q954H, N969K
Omicron Pennsylvania 51% 4,463 8,830
BA.2BA.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron South Dakota 50% 17 34
BA.2.12.1BA.2.12.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452Q, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, S704L, N764K, D796Y, Q954H, N969K
Omicron Alabama 49% 270 547
BA.2.12.1BA.2.12.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452Q, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, S704L, N764K, D796Y, Q954H, N969K
Omicron North Carolina 48% 6,630 13,718
BA.2.12.1BA.2.12.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452Q, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, S704L, N764K, D796Y, Q954H, N969K
Omicron Iowa 48% 597 1,241
BA.2.12.1BA.2.12.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452Q, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, S704L, N764K, D796Y, Q954H, N969K
Omicron New Jersey 46% 7,066 15,233
BA.2.12.1BA.2.12.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452Q, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, S704L, N764K, D796Y, Q954H, N969K
Omicron Georgia 46% 1,725 3,768
BA.2.12.1BA.2.12.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452Q, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, S704L, N764K, D796Y, Q954H, N969K
Omicron Connecticut 44% 3,041 6,854
BA.2.12.1BA.2.12.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452Q, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, S704L, N764K, D796Y, Q954H, N969K
Omicron Florida 44% 7,597 17,238
BA.2BA.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Washington 44% 6,021 13,680
BA.2.12.1BA.2.12.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452Q, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, S704L, N764K, D796Y, Q954H, N969K
Omicron Michigan 44% 2,538 5,791
BA.2.12.1BA.2.12.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452Q, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, S704L, N764K, D796Y, Q954H, N969K
Omicron Indiana 44% 965 2,203
BA.2.12.1BA.2.12.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452Q, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, S704L, N764K, D796Y, Q954H, N969K
Omicron Virginia 44% 3,388 7,765
BA.2.12.1BA.2.12.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452Q, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, S704L, N764K, D796Y, Q954H, N969K
Omicron Maryland 44% 2,848 6,529
BA.2BA.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Rhode Island 43% 930 2,138
BA.2.12.1BA.2.12.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452Q, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, S704L, N764K, D796Y, Q954H, N969K
Omicron Kansas 43% 414 965
BA.2.12.1BA.2.12.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452Q, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, S704L, N764K, D796Y, Q954H, N969K
Omicron Ohio 42% 1,438 3,424
BA.2BA.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Idaho 42% 205 489
BA.2.12.1BA.2.12.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452Q, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, S704L, N764K, D796Y, Q954H, N969K
Omicron Wyoming 42% 70 168
BA.2BA.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Wisconsin 42% 1,843 4,425
BA.2BA.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Massachusetts 41% 5,702 13,860
BA.2BA.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Missouri 40% 633 1,579
BA.2BA.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Colorado 40% 4,497 11,218
BA.2BA.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Tennessee 40% 416 1,042
BA.2BA.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Delaware 40% 437 1,105
BA.2.12.1BA.2.12.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452Q, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, S704L, N764K, D796Y, Q954H, N969K
Omicron District of Columbia 40% 1,780 4,501
BA.2.12.1BA.2.12.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452Q, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, S704L, N764K, D796Y, Q954H, N969K
Omicron Montana 39% 137 348
BA.2.12.1BA.2.12.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452Q, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, S704L, N764K, D796Y, Q954H, N969K
Omicron Arizona 39% 2,107 5,379
BA.2.12.1BA.2.12.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452Q, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, S704L, N764K, D796Y, Q954H, N969K
Omicron West Virginia 39% 242 619
BA.2.12.1BA.2.12.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452Q, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, S704L, N764K, D796Y, Q954H, N969K
Omicron Louisiana 39% 737 1,891
BA.2BA.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Oregon 39% 1,275 3,295
BA.2BA.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Minnesota 39% 1,668 4,319
BA.2BA.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Nevada 38% 1,024 2,670
BA.2BA.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Oklahoma 38% 49 128
BA.2BA.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Illinois 38% 3,230 8,486
BA.2BA.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron California 38% 15,331 40,325
BA.2BA.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Utah 38% 2,653 6,994
BA.2.12.1BA.2.12.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452Q, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, S704L, N764K, D796Y, Q954H, N969K
Omicron Texas 38% 4,862 12,916
BA.2.12.1BA.2.12.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452Q, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, S704L, N764K, D796Y, Q954H, N969K
Omicron New Hampshire 38% 280 744
BA.2.12.1BA.2.12.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452Q, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, S704L, N764K, D796Y, Q954H, N969K
Omicron Mississippi 37% 234 626
BA.2BA.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Maine 37% 395 1,062
BA.2BA.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Hawaii 37% 1,221 3,311
BA.2BA.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Kentucky 37% 312 853
BA.2.12.1BA.2.12.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452Q, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, S704L, N764K, D796Y, Q954H, N969K
Omicron Kentucky 37% 312 853
BA.2BA.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron New Mexico 35% 276 779
BA.2BA.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Alaska 35% 175 497
BA.2.12.1BA.2.12.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452Q, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, S704L, N764K, D796Y, Q954H, N969K
Omicron Arkansas 35% 103 296
BA.2BA.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Nebraska 34% 727 2,118
BA.2.12.1BA.2.12.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452Q, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, S704L, N764K, D796Y, Q954H, N969K
Omicron North Dakota 34% 499 1,458
BA.2.12BA.2.12 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S (79%), K417N (77%), S477N (63%), T478K (64%), E484A (64%), Q493R (64%), Q498R (63%), N501Y (64%), Y505H (64%)
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, S704L, N764K, D796Y, Q954H, N969K
Omicron Vermont 34% 673 1,983
*Criteria: Minimum of 20 samples per state.
Lineage WHO Label Country 2-Week Period Change Previous Support Current Support
BA.2.12.1BA.2.12.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452Q, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, S704L, N764K, D796Y, Q954H, N969K
Omicron Sweden 2022-06-13 8% -> 68% (+60%) 27 / 343 15 / 22
BA.5BA.5 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Netherlands 2022-05-30 12% -> 39% (+28%) 181 / 1,568 550 / 1,398
BA.5BA.5 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Portugal 2022-05-16 37% -> 64% (+27%) 432 / 1,164 709 / 1,101
BA.5BA.5 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Spain 2022-06-13 38% -> 64% (+25%) 546 / 1,419 14 / 22
BA.5BA.5 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Denmark 2022-05-30 6% -> 31% (+24%) 325 / 5,113 1,758 / 5,716
BA.5BA.5 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Germany 2022-05-30 8% -> 32% (+24%) 1,107 / 14,593 3,546 / 11,182
BA.5BA.5 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Norway 2022-05-30 8% -> 32% (+24%) 49 / 597 64 / 199
BA.2BA.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Romania 2022-05-16 67% -> 90% (+24%) 20 / 30 19 / 21
BA.5BA.5 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Ireland 2022-05-30 14% -> 38% (+24%) 112 / 804 213 / 566
BA.5BA.5 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Belgium 2022-05-30 11% -> 34% (+23%) 182 / 1,672 667 / 1,946
BA.5BA.5 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron France 2022-05-30 10% -> 33% (+23%) 396 / 3,935 853 / 2,550
BA.5BA.5 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Slovenia 2022-05-30 7% -> 30% (+22%) 19 / 269 47 / 159
BA.5BA.5 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Luxembourg 2022-05-30 18% -> 40% (+22%) 228 / 1,262 228 / 573
BA.5BA.5 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron United Kingdom 2022-05-30 7% -> 25% (+18%) 531 / 7,442 2,025 / 8,085
BA.5BA.5 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Italy 2022-05-30 6% -> 21% (+15%) 66 / 1,123 286 / 1,358
BA.5BA.5 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Switzerland 2022-05-16 3% -> 15% (+12%) 29 / 933 136 / 919
BA.2BA.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Greece 2022-04-18 62% -> 73% (+11%) 119 / 193 187 / 256
BA.5BA.5 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Estonia 2022-05-16 1% -> 11% (+10%) 3 / 378 38 / 338
BA.5BA.5 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Czechia 2022-05-30 2% -> 12% (+10%) 8 / 454 29 / 240
BA.2BA.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Poland 2022-04-18 38% -> 47% (+10%) 204 / 542 94 / 199
UnassignedUnassigned Mutations
ProteinMutations
Spike (RBD)N501Y (62%)
Spike (non-RBD)D614G (89%), P681H (63%)
NA Austria 2022-04-18 70% -> 78% (+8%) 3,891 / 5,566 4,259 / 5,489
BA.2BA.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Russia 2022-05-16 84% -> 91% (+6%) 102 / 121 108 / 119
BA.2BA.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Turkey 2022-05-02 84% -> 90% (+6%) 649 / 769 236 / 262
BA.5BA.5 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Finland 2022-05-16 1% -> 5% (+4%) 3 / 417 11 / 227
BA.5BA.5 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Slovakia 2022-05-16 0% -> 4% (+4%) 1 / 677 6 / 147
BA.2.9BA.2.9 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Republic of Serbia 2022-05-02 1% -> 4% (+2%) 1 / 79 6 / 162
*Criteria: >= +5% or >= 2x fold change between 2 week periods with >= 20 samples.
Lineage WHO Label Country 2-Week Period Change Previous Support Current Support
BA.2.12.1BA.2.12.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452Q, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, S704L, N764K, D796Y, Q954H, N969K
Omicron Sint Maarten 2022-05-30 9% -> 71% (+61%) 6 / 64 17 / 24
BA.5BA.5 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Martinique 2022-05-30 36% -> 65% (+29%) 19 / 53 24 / 37
BA.2BA.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Guatemala 2022-05-16 18% -> 47% (+29%) 8 / 44 15 / 32
BA.2.12.1BA.2.12.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452Q, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, S704L, N764K, D796Y, Q954H, N969K
Omicron Puerto Rico 2022-05-02 16% -> 41% (+25%) 28 / 172 76 / 186
BA.2.12.1BA.2.12.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452Q, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, S704L, N764K, D796Y, Q954H, N969K
Omicron United States 2022-05-02 27% -> 43% (+16%) 16,820 / 61,255 31,539 / 73,031
BA.2.9BA.2.9 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Mexico 2022-04-18 12% -> 24% (+12%) 35 / 300 99 / 414
BA.2BA.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Canada 2022-06-13 29% -> 38% (+10%) 677 / 2,373 21 / 55
UnassignedUnassigned Mutations
ProteinMutations
Spike (RBD)N501Y (62%)
Spike (non-RBD)D614G (89%), P681H (63%)
NA Panama 2022-04-18 1% -> 11% (+10%) 1 / 80 9 / 83
BA.2.9BA.2.9 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Costa Rica 2022-04-18 30% -> 39% (+9%) 48 / 161 84 / 218
*Criteria: >= +5% or >= 2x fold change between 2 week periods with >= 20 samples.
Lineage WHO Label Country 2-Week Period Change Previous Support Current Support
BA.5BA.5 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Singapore 2022-05-30 8% -> 34% (+26%) 51 / 678 235 / 693
BA.2BA.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Laos 2022-04-18 30% -> 55% (+25%) 12 / 40 18 / 33
BA.5BA.5 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Indonesia 2022-05-30 15% -> 39% (+24%) 24 / 161 89 / 227
BA.5BA.5 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Israel 2022-05-30 7% -> 31% (+24%) 254 / 3,417 1,998 / 6,355
UnassignedUnassigned Mutations
ProteinMutations
Spike (RBD)N501Y (62%)
Spike (non-RBD)D614G (89%), P681H (63%)
NA South Korea 2022-05-30 29% -> 53% (+24%) 789 / 2,707 180 / 341
BA.2BA.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Nepal 2022-05-30 78% -> 100% (+22%) 25 / 32 24 / 24
BA.2BA.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Iran 2022-04-18 20% -> 41% (+21%) 22 / 111 46 / 112
BA.2.12.1BA.2.12.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452Q, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, S704L, N764K, D796Y, Q954H, N969K
Omicron Philippines 2022-04-18 2% -> 23% (+21%) 1 / 44 15 / 65
BA.5BA.5 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Japan 2022-05-30 1% -> 19% (+18%) 52 / 4,085 22 / 117
BA.2.14BA.2.14 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (86%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24- (85%), P25- (85%), P26- (85%), A27S (86%), W64L, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Pakistan 2022-06-13 6% -> 22% (+16%) 3 / 50 5 / 23
BA.2BA.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Cambodia 2022-04-18 21% -> 35% (+14%) 12 / 57 11 / 31
BA.2.2BA.2.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K, I1221T
Omicron Hong Kong 2022-05-30 21% -> 34% (+14%) 39 / 190 70 / 204
BA.2BA.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Vietnam 2022-05-16 29% -> 42% (+13%) 18 / 63 21 / 50
BA.2BA.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron India 2022-06-13 78% -> 88% (+10%) 967 / 1,233 30 / 34
BA.2BA.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Thailand 2022-04-18 49% -> 56% (+7%) 182 / 375 450 / 809
*Criteria: >= +5% or >= 2x fold change between 2 week periods with >= 20 samples.
Lineage WHO Label Country 2-Week Period Change Previous Support Current Support
BA.2.3BA.2.3 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (86%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Solomon Islands 2022-04-18 25% -> 55% (+30%) 5 / 20 55 / 100
BA.5BA.5 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Australia 2022-06-13 10% -> 22% (+12%) 215 / 2,164 37 / 172
BA.2BA.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron New Zealand 2022-04-18 55% -> 61% (+6%) 404 / 731 493 / 802
*Criteria: >= +5% or >= 2x fold change between 2 week periods with >= 20 samples.
Lineage WHO Label Country 2-Week Period Change Previous Support Current Support
BA.2BA.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Ecuador 2022-04-18 4% -> 36% (+32%) 1 / 25 8 / 22
BA.2BA.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Paraguay 2022-05-02 19% -> 50% (+31%) 4 / 21 42 / 84
BA.5BA.5 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Aruba 2022-05-30 5% -> 34% (+29%) 3 / 57 10 / 29
BA.2.3BA.2.3 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (86%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Argentina 2022-04-18 9% -> 33% (+24%) 4 / 47 16 / 49
BA.2BA.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Peru 2022-04-18 31% -> 52% (+21%) 45 / 143 90 / 172
UnassignedUnassigned Mutations
ProteinMutations
Spike (RBD)N501Y (62%)
Spike (non-RBD)D614G (89%), P681H (63%)
NA Colombia 2022-05-16 6% -> 24% (+18%) 17 / 277 44 / 180
BA.2.12.1BA.2.12.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452Q, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, S704L, N764K, D796Y, Q954H, N969K
Omicron Chile 2022-05-30 15% -> 32% (+18%) 111 / 760 26 / 80
BA.5BA.5 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Brazil 2022-05-30 6% -> 21% (+15%) 90 / 1,453 178 / 830
BA.2BA.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Trinidad And Tobago 2022-04-18 28% -> 38% (+10%) 8 / 29 20 / 53
BA.2.12.1BA.2.12.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452Q, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, S704L, N764K, D796Y, Q954H, N969K
Omicron Curacao 2022-05-30 5% -> 14% (+9%) 3 / 57 8 / 56
BA.2.7BA.2.7 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (67%), S477N (72%), T478K (72%), E484A (72%), Q493R (72%), Q498R (72%), N501Y (72%), Y505H (72%)
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Bonaire 2022-05-02 9% -> 17% (+9%) 3 / 35 5 / 29
*Criteria: >= +5% or >= 2x fold change between 2 week periods with >= 20 samples.
Lineage WHO Label Country 2-Week Period Change Previous Support Current Support
BA.4BA.4 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)V3G (55%), T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Ghana 2022-05-30 10% -> 44% (+34%) 4 / 40 14 / 32
BA.2.23BA.2.23 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Botswana 2022-04-18 8% -> 38% (+30%) 2 / 26 8 / 21
UnassignedUnassigned Mutations
ProteinMutations
Spike (RBD)N501Y (62%)
Spike (non-RBD)D614G (89%), P681H (63%)
NA Mauritius 2022-05-16 10% -> 33% (+23%) 21 / 200 19 / 57
BA.4BA.4 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)V3G (55%), T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron South Africa 2022-04-18 38% -> 59% (+21%) 325 / 861 897 / 1,532
BA.2BA.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Eswatini 2022-04-18 19% -> 31% (+13%) 5 / 27 23 / 74
BA.2BA.2 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K (84%), S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Kenya 2022-05-16 15% -> 26% (+11%) 3 / 20 22 / 85
*Criteria: >= +5% or >= 2x fold change between 2 week periods with >= 20 samples.
Lineage WHO Label State 2-Week Period Change Previous Support Current Support
BA.5BA.5 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Arkansas 2022-05-30 1% -> 49% (+48%) 1 / 75 46 / 93
BA.2.12.1BA.2.12.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452Q, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, S704L, N764K, D796Y, Q954H, N969K
Omicron Vermont 2022-05-16 18% -> 55% (+37%) 93 / 506 118 / 215
BA.2.12.1BA.2.12.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452Q, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, S704L, N764K, D796Y, Q954H, N969K
Omicron Idaho 2022-05-02 12% -> 46% (+34%) 12 / 101 28 / 61
BA.2.12.1BA.2.12.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452Q, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, S704L, N764K, D796Y, Q954H, N969K
Omicron Massachusetts 2022-05-16 33% -> 63% (+30%) 1,095 / 3,338 634 / 1,014
BA.2.12.1BA.2.12.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452Q, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, S704L, N764K, D796Y, Q954H, N969K
Omicron Mississippi 2022-05-02 15% -> 44% (+29%) 14 / 92 74 / 168
BA.2.12.1BA.2.12.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452Q, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, S704L, N764K, D796Y, Q954H, N969K
Omicron South Carolina 2022-04-18 17% -> 45% (+28%) 33 / 196 120 / 265
BA.2.12.1BA.2.12.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452Q, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, S704L, N764K, D796Y, Q954H, N969K
Omicron Rhode Island 2022-05-02 22% -> 49% (+27%) 121 / 555 228 / 467
BA.2.12.1BA.2.12.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452Q, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, S704L, N764K, D796Y, Q954H, N969K
Omicron West Virginia 2022-05-02 17% -> 41% (+24%) 20 / 120 110 / 268
BA.2.12.1BA.2.12.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452Q, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, S704L, N764K, D796Y, Q954H, N969K
Omicron Delaware 2022-05-02 31% -> 55% (+24%) 112 / 364 145 / 264
BA.2.12.1BA.2.12.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452Q, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, S704L, N764K, D796Y, Q954H, N969K
Omicron Nebraska 2022-05-16 23% -> 47% (+24%) 121 / 526 225 / 479
BA.2.12.1BA.2.12.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452Q, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, S704L, N764K, D796Y, Q954H, N969K
Omicron Wyoming 2022-05-16 37% -> 61% (+24%) 13 / 35 42 / 69
BA.2.12.1BA.2.12.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452Q, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, S704L, N764K, D796Y, Q954H, N969K
Omicron Arizona 2022-05-02 15% -> 39% (+24%) 139 / 907 499 / 1,280
BA.2.12.1BA.2.12.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452Q, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, S704L, N764K, D796Y, Q954H, N969K
Omicron Montana 2022-05-16 27% -> 49% (+23%) 22 / 82 47 / 95
BA.2.12.1BA.2.12.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452Q, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, S704L, N764K, D796Y, Q954H, N969K
Omicron Missouri 2022-05-16 33% -> 56% (+23%) 147 / 442 169 / 303
BA.2.12BA.2.12 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S (79%), K417N (77%), S477N (63%), T478K (64%), E484A (64%), Q493R (64%), Q498R (63%), N501Y (64%), Y505H (64%)
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, S704L, N764K, D796Y, Q954H, N969K
Omicron Maine 2022-04-18 0% -> 23% (+22%) 1 / 254 76 / 333
BA.5BA.5 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Tennessee 2022-05-30 14% -> 36% (+22%) 19 / 135 20 / 55
BA.2.12.1BA.2.12.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452Q, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, S704L, N764K, D796Y, Q954H, N969K
Omicron Alabama 2022-05-02 24% -> 46% (+22%) 5 / 21 47 / 102
BA.2.12.1BA.2.12.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452Q, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, S704L, N764K, D796Y, Q954H, N969K
Omicron Kansas 2022-04-18 21% -> 43% (+22%) 22 / 103 91 / 212
BA.2.12.1BA.2.12.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452Q, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, S704L, N764K, D796Y, Q954H, N969K
Omicron Oklahoma 2022-05-02 29% -> 50% (+21%) 8 / 28 16 / 32
BA.2.12.1BA.2.12.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452Q, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, S704L, N764K, D796Y, Q954H, N969K
Omicron New Hampshire 2022-05-16 41% -> 62% (+21%) 46 / 112 59 / 95
BA.5BA.5 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Oregon 2022-06-13 8% -> 29% (+21%) 17 / 223 6 / 21
BA.2.12.1BA.2.12.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452Q, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, S704L, N764K, D796Y, Q954H, N969K
Omicron New Jersey 2022-05-02 33% -> 54% (+21%) 993 / 2,980 2,283 / 4,210
BA.2.12.1BA.2.12.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452Q, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, S704L, N764K, D796Y, Q954H, N969K
Omicron Louisiana 2022-04-18 8% -> 28% (+20%) 14 / 180 77 / 276
BA.2.12.1BA.2.12.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452Q, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, S704L, N764K, D796Y, Q954H, N969K
Omicron North Dakota 2022-05-16 23% -> 43% (+20%) 76 / 328 156 / 361
BA.2.12.1BA.2.12.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452Q, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, S704L, N764K, D796Y, Q954H, N969K
Omicron New Mexico 2022-04-18 6% -> 25% (+20%) 15 / 266 72 / 285
BA.2.12.1BA.2.12.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452Q, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, S704L, N764K, D796Y, Q954H, N969K
Omicron Kentucky 2022-05-16 42% -> 61% (+19%) 144 / 341 81 / 133
BA.2.12.1BA.2.12.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452Q, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, S704L, N764K, D796Y, Q954H, N969K
Omicron District of Columbia 2022-05-02 30% -> 49% (+19%) 256 / 851 584 / 1,199
BA.2.12.1BA.2.12.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452Q, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, S704L, N764K, D796Y, Q954H, N969K
Omicron Indiana 2022-05-16 44% -> 63% (+18%) 316 / 715 314 / 502
BA.2.12.1BA.2.12.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452Q, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, S704L, N764K, D796Y, Q954H, N969K
Omicron Wisconsin 2022-05-02 19% -> 36% (+18%) 218 / 1,178 447 / 1,231
BA.2.12.1BA.2.12.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452Q, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, S704L, N764K, D796Y, Q954H, N969K
Omicron Virginia 2022-04-18 17% -> 34% (+18%) 179 / 1,080 678 / 1,974
BA.2.12.1BA.2.12.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452Q, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, S704L, N764K, D796Y, Q954H, N969K
Omicron Pennsylvania 2022-05-02 37% -> 55% (+18%) 649 / 1,746 1,198 / 2,181
BA.2.12.1BA.2.12.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452Q, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, S704L, N764K, D796Y, Q954H, N969K
Omicron Georgia 2022-05-02 30% -> 48% (+18%) 226 / 742 361 / 750
BA.2.12.1BA.2.12.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452Q, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, S704L, N764K, D796Y, Q954H, N969K
Omicron Ohio 2022-04-18 17% -> 34% (+18%) 108 / 639 339 / 983
BA.2.12.1BA.2.12.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452Q, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, S704L, N764K, D796Y, Q954H, N969K
Omicron Texas 2022-04-18 5% -> 23% (+18%) 97 / 1,790 482 / 2,102
BA.2.12.1BA.2.12.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452Q, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, S704L, N764K, D796Y, Q954H, N969K
Omicron Connecticut 2022-05-02 34% -> 51% (+17%) 529 / 1,568 993 / 1,958
BA.2.12.1BA.2.12.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452Q, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, S704L, N764K, D796Y, Q954H, N969K
Omicron Hawaii 2022-05-16 36% -> 53% (+16%) 319 / 877 304 / 575
BA.2.12.1BA.2.12.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452Q, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, S704L, N764K, D796Y, Q954H, N969K
Omicron California 2022-05-02 19% -> 35% (+16%) 1,556 / 8,196 3,534 / 9,976
BA.2.12.1BA.2.12.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452Q, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, S704L, N764K, D796Y, Q954H, N969K
Omicron Florida 2022-05-02 28% -> 44% (+16%) 849 / 3,035 1,477 / 3,334
BA.2.12.1BA.2.12.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452Q, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, S704L, N764K, D796Y, Q954H, N969K
Omicron Illinois 2022-05-02 26% -> 42% (+16%) 470 / 1,813 993 / 2,353
BA.2.12.1BA.2.12.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452Q, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, S704L, N764K, D796Y, Q954H, N969K
Omicron Michigan 2022-04-18 16% -> 32% (+16%) 151 / 959 328 / 1,034
BA.2.12.1BA.2.12.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452Q, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, S704L, N764K, D796Y, Q954H, N969K
Omicron Maryland 2022-05-16 46% -> 62% (+16%) 831 / 1,794 1,010 / 1,631
BA.2.12.1BA.2.12.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452Q, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, S704L, N764K, D796Y, Q954H, N969K
Omicron Minnesota 2022-05-02 15% -> 31% (+15%) 143 / 940 332 / 1,082
BA.2.12.1BA.2.12.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452Q, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, S704L, N764K, D796Y, Q954H, N969K
Omicron Washington 2022-05-16 23% -> 38% (+15%) 705 / 3,051 1,181 / 3,092
BA.4BA.4 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)V3G (55%), T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron North Carolina 2022-06-13 5% -> 20% (+15%) 75 / 1,595 18 / 91
BA.2.12.1BA.2.12.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452Q, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, S704L, N764K, D796Y, Q954H, N969K
Omicron Iowa 2022-04-18 30% -> 43% (+14%) 51 / 171 159 / 366
BA.2.12.1BA.2.12.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452Q, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, S704L, N764K, D796Y, Q954H, N969K
Omicron New York 2022-04-18 34% -> 48% (+14%) 2,959 / 8,616 4,004 / 8,355
BA.5BA.5 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, H69-, V70-, G142D, V213G, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K
Omicron Nevada 2022-05-30 6% -> 19% (+13%) 36 / 646 82 / 432
BA.2.12.1BA.2.12.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452Q, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, S704L, N764K, D796Y, Q954H, N969K
Omicron Colorado 2022-05-16 29% -> 42% (+13%) 719 / 2,519 1,333 / 3,188
BA.2.12BA.2.12 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S (79%), K417N (77%), S477N (63%), T478K (64%), E484A (64%), Q493R (64%), Q498R (63%), N501Y (64%), Y505H (64%)
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, S704L, N764K, D796Y, Q954H, N969K
Omicron Alaska 2022-05-02 3% -> 14% (+11%) 2 / 69 16 / 112
BA.2.12.1BA.2.12.1 (Omicron) Mutations
ProteinMutations
Spike (RBD)G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452Q, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H
Spike (non-RBD)T19I, L24-, P25-, P26-, A27S, G142D, V213G, D614G, H655Y, N679K, P681H, S704L, N764K, D796Y, Q954H, N969K
Omicron Utah 2022-05-02 18% -> 28% (+10%) 144 / 818 475 / 1,722
*Criteria: >= +5% or >= 2x fold change between 2-week periods with >= 20 samples.

Data Timeline

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Dashboard Timeline

January 07, 2022
04:30PM

Top/emerging variant graphs updated

Added overlays and country-specific information to variant graphs
November 27, 2021
01:30PM

WHO Labels Updated

Added Omicron WHO variant
November 18, 2021
04:30PM

Dashboard UI/graphs updated

Added WHO labels to lineages
April 16, 2021
08:50PM

Dashboard UI/graphs updated

Added emerging lineages tracking and top lineages tracking per US state to home page
April 16, 2021
08:00PM

Dashboard backend pipeline overhauled

Overhauled backend pipeline to automatically download and QC data from GISAID daily
April 05, 2021
03:30PM

Dashboard UI/graphs updated

Added top and emerging lineage maps and graphs. Overhauled home page
March 23, 2021
06:00PM

Dashboard performance overhauled

Added caching and refactored all graphs for performance before public release
November 13, 2020
04:00PM

Dashboard UI/graphs updated

Broad-scale update across the entire dashboard to prepare for its launch onto the world wide web!
June 15, 2020
12:00AM

Dashboard graphs upgraded

Migrated dashboard graphs from Plotly to ECharts
June 04, 2020
08:06PM

Dashboard data source changed

Upgraded dashboard to use a database vs flat files. 3x reduction in load time
June 02, 2020
12:18PM

Dashboard UI upgraded

Overhauled dashboard user interface to use bs4dash
May 26, 2020
12:00AM

Variant tracking expanded

Began tracking variants in genes ORF1a and ORF1b
May 11, 2020
12:00AM

Variant tracking expanded

Began tracking variants in genes E, M, N, ORF3a, ORF7a, ORF8, and ORF10
April 27, 2020
12:00AM

Phylogenetic analysis added

Added tab containing viral genome evolutionary relationships
April 03, 2020
12:00AM

Automated QC pipeline created

Cleans up metadata fields such as age, collection date, gender, etc
April 02, 2020
10:36AM

First version of dashboard created

Created first version with shinydashboard. Data is ingested from flat files
March 31, 2020
12:00AM

Patient metadata tracking started

Began downloading patient metadata for all genomes
January 10, 2020
12:00AM

First data downloaded

Began downloading genomes from GISAID and subsequent variant calling
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